Microfluidic nanoparticle concentration utilizes miniaturized devices and precisely manipulated fluids to concentrate nanoparticles for enhanced detection and analysis. It capitalizes on the unique properties of nanoparticles, including their large surface area, optical characteristics, and reactivity. By combining microfluidics and nanoparticle technologies, it offers precise control over fluid flow, enabling efficient nanoparticle capture and enrichment. This approach holds great promise for improving sensitivity and specificity in disease diagnostics and various biomedical applications.