Acetaminophen, a common analgesic, exhibits a temperature-dependent solubility in water. As temperature increases, its solubility increases nonlinearly, evident in the solubility curve. The saturation concentration, representing the maximum amount of acetaminophen that can dissolve in water at a given temperature, is crucial in pharmaceutical formulations and drug delivery. Understanding the thermodynamics of solubility, including enthalpy, entropy, and Gibbs free energy, is essential for predicting acetaminophen’s solubility behavior.
