Nitrite, a small inorganic ion (NO2-), holds significant biological importance. As an intermediate in the nitrogen cycle, it plays a role in cellular processes through interactions with nitrite reductase and nitrosylating agents. Nitrite’s vasodilatory properties contribute to endothelial function and blood vessel health. However, excessive nitrite exposure can lead to harmful effects, including methemoglobinemia, cyanosis, and toxicity. Understanding the charge of nitrite and its interactions is crucial for comprehending its role in various biological and physiological processes.
